Aim. To identify a perspectives for using a single incision laparoscopic technologies in surgery.

Materials and methods: Today we have a several questions relating to a single incision laparoscopic surgery such as the possible spectrum of their application, safety and economic efficiency. The main is: does this technologies have a perspectives in future.

In paper was performed a retro and prospective analysis of the data of modern literature and authors own experience in surgical treatment using a single incision laparoscopic technologies.

Results: The study included 74 patients who underwent: cholecystectomy – 64 (86,5%), nephrectomy – 4 (5,4%), ovarian cyst removal – 4 (5,4%), kidney resection – 2 (2,7 %), using various kind of ports: “X-Cone Karl Storz” (28), “Covidien” (18), “PPP” (7), and 21 cases of multi-trocar access.

Conclusions: Our opinion that the perspectives for the development of single incision laparoscopy, is the further development of endoscopic devices, including robotic ones, and we believe that it will be a real future and endoscopic surgeons should be ready for this.

There are patients suffered prostate cancer and diagnosed with stone disease in urological centres. These cases represent non-standard issue of choosing the optimal surgical treatment. Currently clinical recommendations haven’t described the particular answer for this answer yet. There is also lack of information published in literature foсused on the issue.

Aim of the study was to determine the optimal choice of surgical treatment for patients diagnosed with stone disease and prostate cancer.

Materials and methods: Retrospective study of patients diagnosed with prostate cancer and stone disease for the period from 2006 to 2019 was performed. Among 2047 in-patient cases of prostate cancer 71 patients with stone disease were included.

Results: 49 of 71 (69%) patients diagnosed with stone disease had indications for surgical treatment at the moment of hospitalisation. Stages of prostate cancer in this group were T1-T2 (91,7%) and T3(8,3%). 25 patients (51%) had kidney stone disease, 23 patients (47%) – ureter stone disease and only 1 patient – kidney and ureter stone disease. 37 patients (75%) presented complains related to stone disease, other cases (25%) were asymptomatic. Surgical treatment of stone disease primarily was performed in the majority of cases (72,2%). Surgical treatment of prostate cancer subsequently included radical prostatectomy in most cases 7 (86,1%). Simultaneous surgical treatment of both diseases haven’t performed in this study.

Conclusion: The main factors influencing the decision making of optimal surgical treatment for this group of patients were clinical presentation and group of prostate cancer risk.

The work is based on the analysis of clinical cases of the incidence of intestinal coronavirus infection in the conditions of the clinic of the Bashkir State Medical University for the period from April to November 2020. The aim of the study is to elucidate the pathogenetic mechanisms of development, the peculiarities of the clinical course and effective methods of treating this disease. In these clinical cases, the positive effect of conservative therapy is noted, which confirms the absence of the need for aggressive surgical tactics.

Nowadays formal programs for screening of early cancer and precancerous conditions of the gastric mucosa exist only in Japan and South Korea, where studies of the upper gastrointestinal are carried out in people at the age of 40 and older.

Objective of the study: to assess the condition of the gastric mucosa in 40-50 year-old patients by means of determination of pepsinogen 1 and pepsinogen 2 concentration ratio, and esophagogastroduodenoscopy complemented by biopsy.

Materials and methods. The analysis included examination results of 23 patients with the diagnosis: "unspecified dyspepsia". Gender distribution of patients: women – 12, men – 11, average age 46 + 3.6 years (M + m). It was a single-stage study. All patients underwent video esophagogastroduodenoscopy. There were also taken two biopsy samples, from the antrum and the body of the stomach, for a rapid urease test, and then the patients underwent blood sampling. Inclusion criteria: patients with dyspeptic symptoms who have not been previously examined and have not received any treatment; aged 40 to 50 years; voluntary informed consent for examination, positive result of rapid urease test. Withdrawal criteria: refusal to participate in the study, duodenal ulcer.

Results. Atrophic gastritis was identified during endoscopic and morphological examination in three patients (out of 23) with gastric ulcers, but the concentration ratio of pepsinogen 1 and pepsinogen 2 was higher than 3/1.

Conclusion. Our study has shown that determination of concentration ratio of pepsinogen 1 and pepsinogen 2 in patients under 50 does not reflect the presence of atrophic changes in the mucous membrane.

Purpose. To analyze short-term and long-term outcomes of surgical treatment of the patients with hiatal hernia complicated by gastroesophageal reflux disease, depending on the choice of fundoplication method.

Materials and methods. A retrospective analysis of the short and long-term outcomes of the treatment of 171 patients suffering hiatal hernia complicated by gastroesophageal reflux disease was performed. All patients were underwent laparoscopic hiatal hernia repair supplemented by Nissen fundoplication - 109 patients or Toupet fundoplication – 62 patients.

Results. In the Nissen fundoplication group the incidence of intraoperative complications was 9.2% (11 patients), postoperative complications – 8.3% (9 patients), dysphagia in the early postoperative period was noted in 24 (22%) patients. In 5 years after surgery, gastroesophageal reflux was observed in 6 (5.5%) patients, anatomical recurrence in 13 (11.9%) patients. Dysphagia in the late postoperative period was noted in 7.3% (8 patients). In the Toupet fun doplication group the incidence of intraoperative complications was 11.3% (7 patients), the incidence of postoperative complications was 6.5% (4 patients), functional dysphagia in the early postoperative period was noted in 8 (12.9%) patients. In 5 years after surgery, gastroesophageal reflux was observed in 8 (12.9%) patients, anatomical relapse in 13 (11.9%) patients. Persistent long-term dysphagia in the late postoperative period was noted in 2(3.2%) patients.

Findings. The choice of fundoplication method did not significantly affect on the duration of surgery, the frequency of intraoperative and postoperative complications, duration hospital stay, the incidence of early functional postoperative dysphagia, the number of unsatisfactory results in the long term period, including recurrence and dysphagia.

Purpose of work. Improve patient outcomes in patients with pancreatic cancer.

Material and methods of research. We present our own clinical observation of surgical treatment of malignant neoplasms of the head of the pancreas with invasion of the main venous vessels. In 2019, on the basis of 1 surgical Department of the GUZ Regional clinical oncological dispensary, 2 patients underwent gastropancreatoduodenal resections with circular portal vein resection and end-to-end angioplasty.

The results of the study and their discussion. Tumor invasion into the main venous vessels is not a contraindication to performing radical surgery and is achievable when performing gastropancreatoduodenal resection, due to resections of the main venous vessels together with the tumor invading its wall.

Conclusions. Resection of the portal vein together with the pancreatic head tumor invading its wall contributes to the achievement of radical surgery when performing gastropancreatoduodenal resection.

Aim: To evaluate the medical care quality provided to patients with fecal incontinence in practice; to investigate the patient care effectiveness; to identify the problems the patient and the doctor are faced during the postpartum anal incontinence (AI) treatment.

Methods: A questionnaire for surgeons was created using Google forms. It includes 22 questions about medical characteristics of patients with AI, used diagnostic methods, and treatment results. The answers were analyzed and presented as histograms.

Results: Totally 134 (17.4%) questionnaires were completed from September to November 2020. Labor was the most common AI cause (74.4%). The median age was 20-40 years, 37% of patients was >40 years, 8% – >60 years. The most common complaints were incontinence (70%) and decreased life quality (72%). Rectovaginal fistulas were diagnosed in 28% of cases. The sphincter complex lesion size, age and anorectal manometry results determined the treatment strategy. Only 8.8% of surgeons suggested sacral neurostimulation in case of the other methods inefficiency. Up to 16.7% of patients were offered to create stoma as the final treatment method.

Discussion: Our study is the first major survey for proctologists and surgeons in Russia, assessing the medical care of patients with postpartum AI. The results indicate insufficient attention to this problem; it requires educational and organizational solutions. Regional or federal centers where obstetrician and surgeons can work cooperatively could be extremely helpful to provide appropriate medical care to these patients and to improve the treatment quality for women with postpartum AI.