PERSPECTIVES OF USAGE OSTEOPOROSIS BIOMARKERS IN DIAGNOSTICS AND TREATMENT
https://doi.org/10.17238/issn2223-2427.2019.1.45-47
Abstract
Osteoporosis is a systemic disease characterized by decreased bone mass, deterioration of bone tissue and increased susceptibility to fracture. Today the most of osteoporosis cases are diagnosed by x-ray measuring of bone density. However, there is a tendency of using potential biomarkers for bone formation and degradation diagnostics. The current review observes the main biomarkers of bone remodeling and analyze their possible clinical use. According to the collected data, the most cited markers of bone remodeling was N- and C- collagen telopeptide, showing resorption processes and bone-specific alkaline phosphatase, which reflected the osteoblasts activity, which is increased usually after the fractures. There also was noticed a significant increase in number of published articles. Thus, further studies need to be conducted in order to create and develop new diagnostic techniques and implementing them into clinical practice. Provided with enough attention and resources, future findings will be able to rise the quality of prevention and treatment of osteoporosis.
About the Authors
F. N. Zakirov
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Russian Federation
Moscow, 119991
Russian Federation
Moscow, 119991
A. A. Krasilnikov
State autonomous Educational Institution of Higher Education Moscow City University
Russian Federation
Russian Federation
assistant professor of physical education and training methodology department
Moscow, 129226
E. A. Lubyshev
State autonomous Educational Institution of Higher Education Moscow City University
Russian Federation
Russian Federation
assistant professor of physical education and training methodology department
Moscow, 129226
G. R. Chubanova
State autonomous Educational Institution of Higher Education Moscow City University
Russian Federation
Russian Federation
assistant professor of physical education and training methodology department
Moscow, 129226
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Review
For citations:
Zakirov F.N., Krasilnikov A.A., Lubyshev E.A., Chubanova G.R. PERSPECTIVES OF USAGE OSTEOPOROSIS BIOMARKERS IN DIAGNOSTICS AND TREATMENT. Surgical practice (Russia). 2019;(1):45-47. (In Russ.) https://doi.org/10.17238/issn2223-2427.2019.1.45-47
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