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Role of peroral cholangioscopy in the diagnosis of primary sclerosing cholangitis

https://doi.org/10.5922/2223-2427-2025-10-1-7

Abstract

Aim. To demonstrate the therapeutic and diagnostic capabilities of peroral cholangioscopy in the diagnosis and symptomatic treatment of primary sclerosing cholangitis.

Materials and methods. Due to the presence of undifferentiated stricture, according to instrumental examination methods, peroral cholangioscopy was performed in the presented case. The SpyGlass DS II (Boston Scientific) biliary tract endoscopic imaging system was used as a daughter device. Intraductal biopsy was performed using SpyBite Max forceps. Taking into account the visual picture of intrahepatic cholangiolithiasis, large stones, contact laser lithotripsy using a thulium laser was performed for curative purposes.

Results. Visual examination of the biliary tree and intra-flow biopsy confirmed the diagnosis of primary sclerosing cholangitis. The use of contact laser lithotripsy made it possible to carry out adequate drainage.

Conclusion. The peroral cholangioscopy technique allows for targeted biopsy of altered tissues under double (endoscopic and X-ray) control, is effective and relatively safe in the differential diagnosis of various lesions of the bile ducts.

About the Authors

M. Y. Kurdanova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Madina Y. Kurdanova - Endoscopist, Department of Endoscopy

Kashirskoye highway, 23, Moscow, 115522



O. T. Imaraliev
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Oyatiddin T. Imaraliev - Endoscopist, Department of Endoscopy

Kashirskoye highway, 23, Moscow, 115522



M. E. Timofeev
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Mikhail E. Timofeev - Associate professor, Endoscopist, Department of Endoscopy

Kashirskoye highway, 23, Moscow, 115522



I. A. Karasev
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Ivan A. Karasev - Associate professor, Endoscopist, Department of Endoscopy

Kashirskoye highway, 23, Moscow, 115522



A. A. Salimova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Alina A.Salimova - Endoscopist, Department of Endoscopy

Kashirskoye highway, 23, Moscow, 115522



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Review

For citations:


Kurdanova M.Y., Imaraliev O.T., Timofeev M.E., Karasev I.A., Salimova A.A. Role of peroral cholangioscopy in the diagnosis of primary sclerosing cholangitis. Surgical practice (Russia). 2025;(1):86-95. (In Russ.) https://doi.org/10.5922/2223-2427-2025-10-1-7

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ISSN 2223-2427 (Print)