PARASITIC ABSCESS AS AN INCIDENTAL HISTOLOGICAL FINDING IN THE TREATMENT OF SIGMOID COLON CANCER
https://doi.org/10.38181/2223-2427-2020-3-53-58
Abstract
Background: A high worldwide incidence of colorectal cancer defines the importance of search not only for effective treatment methods, but also for risk factors for the cancer development and its worst prognosis. The influence of many genetic factors, environmental characteristics and lifestyle features has already been proven, and recently the attention of researchers is being focused on the study of microbiota and, in particular, various parasitic intestinal diseases in the context of risk factors for colorectal cancer.
Clinical case presentation: we demonstrate an incidental finding of parasitic invasion signs during the pathomorphological examination of the surgical specimen in a patient without an epidemiological history.
Conclusion: Further studies are needed not only to confirm and substantiate the role of micro- and macroorganisms inhabiting the intestine in the development of oncological diseases, but also to identify individual links of pathogenesis, pathological pathways and signaling molecules involved in carcinogenesis. Research like this could help broaden knowledge about both the risk factors and predictors of colorectal cancer and the potential sites for targeted therapy.
About the Authors
E. A. GalliamovRussian Federation
Eduard A. Galliamov — MD, Professor, Head of the Department of General Surgery
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
Bolshaya Pirogovskaya St., 19/1, 119146, Moscow, Russian Federation
M. A. Agapov
Russian Federation
Mikhail A. Agapov — PhD, Professor at the Department of Surgery
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
P. G. Mal’kov
Russian Federation
Pavel G. Mal’kov — MD, Professor, Head of the Department of Clinical Patology of the Medical Research Educational Center
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
D. R. Markaryan
Russian Federation
Daniil R. Markaryan — PhD, Docent at the Department of Surgery
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
N. V. Danilova
Russian Federation
Natalya V. Danilova — PhD, Senior Researcher at the Department of Clinical Patology of the Medical Research Educational Center
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
V. V. Kakotkin
Russian Federation
Viktor V. Kakotkin — Surgeon at the Department of Surgery №1 of the Medical Research Educational Center
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
E. A. Kazachenko
Russian Federation
Ekaterina A. Kazachenko — Resident at the Department of Surgery of the Faculty of Medicine
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
A. M. Lukyanov
Russian Federation
Aleхander M. Lukyanov — Resident at the Department of Surgery of the Faculty of Medicine
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
N. A. Oleynikova
Russian Federation
Nina A. Oleynikova – PhD, Researcher of the Department of Clinical Pathology of the Medical Research Educational Center
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
V. A. Kubyshkin
Russian Federation
Valery A. Kubyshkin — PhD, academician at RSA, Head of the Surgery Department
Leninskie Gory St., 1, 119991, Moscow, Russian Federation
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Review
For citations:
Galliamov E.A., Agapov M.A., Mal’kov P.G., Markaryan D.R., Danilova N.V., Kakotkin V.V., Kazachenko E.A., Lukyanov A.M., Oleynikova N.A., Kubyshkin V.A. PARASITIC ABSCESS AS AN INCIDENTAL HISTOLOGICAL FINDING IN THE TREATMENT OF SIGMOID COLON CANCER. Surgical practice (Russia). 2020;(3):53-58. (In Russ.) https://doi.org/10.38181/2223-2427-2020-3-53-58