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The possibility of preventing the development of adhesions

https://doi.org/10.5922/2223-2427-2025-10-1-4

Abstract

Aim. To study the possibilities of preventing the development of adhesions in clinical practice.

Methods. The present study analyzed current sources, both domestic and foreign literature on various ways of preventing the development of adhesions and the effectiveness of these methods.

Results. According to the definition of the Association of Surgeons, adhesions are a multifactorial pathological process based on various morphofunctional disorders of organs and body systems. Currently, there are several main ways to reduce the severity of the adhesive process: reduction of injury to the peritoneum, the use of drugs that affect the formation of fibrin and fibrinolysis, effective hemostasis, prevention of tissue drying and the use of barriers that prevent adhesions.

Conclusion. Despite the extensive knowledge of the pathophysiology of adhesions, strategies to address the problem of adhesions have not yet been developed. The methods discussed in this study, although promising, do not show results that would allow their widespread implementation in clinical practice.

About the Authors

A. M. Morozov
Tver State Medical University
Russian Federation

Artem M. Morozov – Associate Professor of the Department of General Surgery

Sovetskaya Str., 4, Tver, 170100



A. N. Sergeev
Tver State Medical University
Russian Federation

Alexey N. Sergeev - Associate Professor, Head of the Department of General Surgery

Sovetskaya Str., 4, Tver, 170100



N. A. Sergeev
Tver State Medical University
Russian Federation

Nikolay A. Sergeev – Professor of the Department of General Surgery

Sovetskaya Str., 4, Tver, 170100



A. A. Bagdasarov
Tver Children’s Regional Clinical Hospital
Russian Federation

Artyom A. Bagdasarov – male nurse

Rybatskaya Str., 13, Tver, 170100



E. S. Petrukhina
Tver State Medical University
Russian Federation

Ekaterina S. Petrukhina – nurse of the general field visiting line brigade

Trekhsvyatskaya Str., 6, Tver, 170100



V. P. Stepanenko
Tver Children’s Regional Clinical Hospital
Russian Federation

Valeria P. Stepanenko – ward nurse

Rybatskaya Str., 13, Tver, 170100



E. A. Fisyuk
Tver State Medical University
Russian Federation

Ekaterina A. Fisyuk – student, Faculty of Pediatrics

Sovetskaya Str., 4, Tver, 170100



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Morozov A.M., Sergeev A.N., Sergeev N.A., Bagdasarov A.A., Petrukhina E.S., Stepanenko V.P., Fisyuk E.A. The possibility of preventing the development of adhesions. Surgical practice (Russia). 2025;(1):46-63. (In Russ.) https://doi.org/10.5922/2223-2427-2025-10-1-4

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