Organ-sparing resection techniques in the treatment of liver echinococcosis
https://doi.org/10.38181/2223-2427-2023-2-1
Abstract
This study aims to present and evaluate the results of treating surgery patients using organsparing resection interventions for liver echinococcosis.
Material and methods. The study presents the results of treating 103 patients (51/49.6 % males, 52/50.6 % females) who have undergone total radical pericystectomy/atypical liver resection for liver echinococcosis. Patients were divided into two groups: Group 1, with interventions performed through laparotomic access (n = 84), and Group 2, with interventions using laparoscopic techniques (n = 19).
Results. In the abdominal intervention group, there was no statistically significant advantage in the rate of parenchyma dissection between different methods (p > 0.05). The average time of haemostasis without the Tachocomb haemostatic substance applied showed a lower value (p = 0.17). The average blood loss during the Pringle manoeuvre was significantly lower (p = 0.043).
There was no statistically significant advantage in the laparoscopic intervention group as regards the rate of parenchyma dissection (p = 0.74). The average haemostasis time was significantly shorter in patients using the Floseal haemostatic matrix than those treated otherwise (p = 0.001). In patients with the improved laparoscopic Pringle manoeuvre, blood loss was significantly less than in those who had not undergone the technique (p = 0.00008).
No statistically significant differences were observed (p = 0.76) when comparing the percentages of nonspecific complications in the two groups. The average value of postoperative bed-day was significantly lower in the laparoscopic surgical treatment group (p = 0.00001).
Conclusion. Using the Pringle maneuver when performing abdominal and laparoscopic interventions statistically proved its effectiveness. The use of the Floseal haemostatic matrix during laparoscopic operations allowed a statistically significant reduction in the time of haemostasis and intraoperative bleeding. The duration of the operation and the time of dissection of the parenchyma in the laparoscopic surgery were significantly higher (p < 0.05). The immediate results of the laparoscopic and abdominal interventions proved comparable.
About the Authors
A. O. KrasnovRussian Federation
Dr. Arkadiy O. Krasnov
22 Ostrovsky St, Kemerovo, 650000
V. V. Anishchenko
Russian Federation
Prof. Vladimir V. Anishchenko
52 Krasny prospect, Novosibirsk, 630091
17/1 Kommunisticheskaya St, Novosibirsk, 630099
I. V. Pachgin
Russian Federation
Dr. Igor V. Pachgin
22 Ostrovsky St, Kemerovo, 650000
K. A. Krasnov
Russian Federation
Dr. Konstantin A. Krasnov
22 Ostrovsky St, Kemerovo, 650000
22a Voroshilova St, Kemerovo, 650056
V. A. Pelts
Russian Federation
Dr. Vladislav A. Pelts
22 Ostrovsky St, Kemerovo, 650000
22a Voroshilova St, Kemerovo, 650056
O. A. Krasnov
Russian Federation
Prof. Oleg A. Krasnov
22a Voroshilova St, Kemerovo, 650056
53/1 Oktyabrsky prospect, Kemerovo, 650066
V. V. Pavlenko
Russian Federation
Prof. Vladimir V. Pavlenko
22 Ostrovsky St, Kemerovo, 650000
22a Voroshilova St, Kemerovo, 650056
References
1. Bayrak M, Altıntas Y. Current approaches in the surgical treatment of liver hydatid disease: single center experience. BMC Surg. 2019. Jul 17;19(1):95. https://doi.org/10.1186/s12893-019-0553-1.
2. Pakala T, Molina M, Wu GY. Hepatic Echinococcal Cysts: A Review. J Clin Transl Hepatol. 2016. Mar 28;4(1):39—46. https://doi.org/10.14218/JCTH.2015.00036.
3. Benkabbou A, Souadka A, Serji B, Hachim H, Mohsine R, Ifrine L, Belkouchi A, El Malki HO. Changing paradigms in the surgical management of cystic liver hydatidosis improve the postoperative outcomes. Surgery. 2016. Apr 159(4):1170—1180. https://doi.org/10.1016/j.surg.2015.10.029.
4. Goja S, Saha SK, Yadav SK, Tiwari A, Soin AS. Surgical approaches to hepatic hydatidosis ranging from partial cystectomy to liver transplantation. Ann Hepatobiliary Pancreat Surg. 2018. Aug 22(3):208—215. https://doi.org/10.14701/ahbps.2018.22.3.208.
5. Dervenis C, Delis S, Avgerinos C, Madariaga J, Milicevic M. Changing concepts in the management of liver hydatid disease. J Gastrointest Surg. 2005. Jul—Aug 9(6):869—877. https://doi.org/10.1016/j.gassur.2004.10.016.
6. Al-Saeedi M, Khajeh E, Hoffmann K, Ghamarnejad O, Stojkovic M, Weber TF, Golriz M, Strobel O, Junghanss T, Büchler MW, Mehrabi A. Standardized endocystectomy technique for surgical treatment of uncomplicated hepatic cystic echinococcosis. PLoS Negl Trop Dis. 2019. Jun 21;13(6):e0007516. https://doi.org/10.1371/journal.pntd.0007516.
7. Chautems R, Buhler L, Gold B, Chilcott M, Morel P, Mentha G. Long term results after complete or incomplete surgical resection of liver hydatid disease. Swiss Med Wkly. 2003. May 3;133(17—18):258—262. https://doi.org/10.4414/smw.2003.10168.
8. Botrugno I, Gruttadauria S, Li Petri S, Cintorino D, Spada M, Di Francesco F, Pagano D, Crino F, Anastasi D, Gridelli B. Complex hydatid cysts of the liver: a single center’s evolving approach to surgical treatment. Am Surg. 2010. Sep 76(9):1011—1015.
9. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205—213. https://doi.org/10.1097/01.sla.0000133083.54934.ae.
10. Rahbari NN, Garden OJ, Padbury R, Maddern G, Koch M, Hugh TJ, Fan ST, Nimura Y, Figueras J, Vauthey JN, Rees M, Adam R, Dematteo RP, Greig P, Usatoff V, Banting S, Nagino M, Capussotti L, Yokoyama Y, Brooke-Smith M, Crawford M, Christophi C, Makuuchi M, Büchler MW, Weitz J. Post-hepatectomy haemorrhage: a definition and grading by the International Study Group of Liver Surgery (ISGLS). HPB (Oxford). 2011;13(8):528—535. https://doi.org/10.1111/j.1477-2574.2011.00319.x.
11. Rahbari NN, Garden OJ, Padbury R, Brooke-Smith M, Crawford M, Adam R, Koch M, Makuuchi M, Dematteo RP, Christophi C, Banting S, Usatoff V, Nagino M, Maddern G, Hugh TJ, Vauthey JN, Greig P, Rees M, Yokoyama Y, Fan ST, Nimura Y, Figueras J, Capussotti L, Büchler MW, Weitz J. Posthepatectomy liver failure: a definition and grading by the International Study Group of Liver Surgery (ISGLS). Surgery. 2011;149(5):713— 724. https://doi.org/10.1016/j.surg.2010.10.001.
12. Koch M, Garden OJ, Padbury R, Rahbari NN, Adam R, Capussotti L, Fan ST, Yokoyama Y, Crawford M, Makuuchi M, Christophi C, Banting S, Brooke-Smith M, Usatoff V, Nagino M, Maddern G, Hugh TJ, Vauthey JN, Greig P, Rees M, Nimura Y, Figueras J, DeMatteo RP, Büchler MW, Weitz J. Bile leakage after hepatobiliary and pancreatic surgery: a definition and grading of severity by the International Study Group of Liver Surgery. Surgery. 2011;149(5):680—688. https://doi.org/10.1016/j.surg.2010.12.002.
Review
For citations:
Krasnov A.O., Anishchenko V.V., Pachgin I.V., Krasnov K.A., Pelts V.A., Krasnov O.A., Pavlenko V.V. Organ-sparing resection techniques in the treatment of liver echinococcosis. Surgical practice (Russia). 2023;(2):6-18. (In Russ.) https://doi.org/10.38181/2223-2427-2023-2-1