BLEBBING OF THE PLASMA MEMBRANE OF LYMPHOCYTES IN THE POSTOPERATIVE PERIOD OF UROLITHIASIS
https://doi.org/10.38181/2223-2427-2022-4-42-47
Abstract
Urolithiasis is an urgent problem of surgical urology, about 200 thousand operations are performed annually in the Russian Federation. The complicated course of the postoperative period is accompanied by changes in homeostasis associated with immune activation and dysregulation of the endothelial system. The study evaluated the parameters of lymphocyte plasma membrane blebbing in patients with complicated and uncomplicated postoperative urolithiasis. 240 patients suffering from urolithiasis took part, who underwent surgical treatment. Patients were divided into two clinical groups: I clinical group (n = 130) – patients with a favorable course of the postoperative period of urolithiasis, II clinical group (n = 110) – patients with a complicated course of the postoperative period of urolithiasis. The control group was – 25 practically healthy persons. Lymphocyte membrane status was assessed by phase contrast microscopy. The maximum frequency of plasma membrane changes was recorded in patients with postoperative complications and amounted to 15.92 [13.20; 17.01] when evaluating initial blebbing and 21.93 [17.67; 30.45] for terminal blebbing. With a favorable course of postoperative period, patients with urolithiasis did not have statistically significant changes in the parameters of blebbing of the plasma membrane of lymphocytes.
About the Authors
A. G. Berezhnoy
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Road hospital at the station Krasnoyarsk Russian Railways
Russian Federation
Russian Federation
Alexandr G. Berezhnoy – Dr. Sci., Professor Department of Urology, Andrology and Sexology
Partizan Zheleznyak Str., 1, Krasnoyarsk, 660022
Head of the Department of Urology
Lomonosova Str., 47, Krasnoyarsk, 660058
С. С. Дунаевская
V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Road hospital at the station Krasnoyarsk Russian Railways
Russian Federation
Russian Federation
Дунаевская Светлана Сергеевна – Dr. Sci., Professor Department of General Surgery, prof.
Partizan Zheleznyak Str., 1, Krasnoyarsk, 660022
Head of the Research Coordination Office
Lomonosova Str., 47, Krasnoyarsk, 660058
Tel.: 89050873585
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Review
For citations:
Berezhnoy A.G., Дунаевская С.С. BLEBBING OF THE PLASMA MEMBRANE OF LYMPHOCYTES IN THE POSTOPERATIVE PERIOD OF UROLITHIASIS. Surgical practice (Russia). 2022;(4):42-47. (In Russ.) https://doi.org/10.38181/2223-2427-2022-4-42-47
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