LAPOROSCOPIC PELVIC EXENTERATION FOR TREATMENT OF PRIMARY MULTIPLE CANCER. CASE REPORT
https://doi.org/10.38181//2223-2427-2021-3-31-39
Abstract
This clinical case represents the experience of surgical treatment of a patient with multiple primary metachronous cancer: 1. Sigmoid cancer рТ4NxM0. Resection of sigmoid colon (16.12.2013). Three courses of adjuvant chemotherapy (XELOX). Recurrence (2015). Laparotomy, Colproctectomy with D3 paraaortic lymph dissection. Ileostomy (2015). One course of chemotherapy (XELOX). 2. Upper tract urothelial carcinoma (right ureter) pT2N0M0R0. Right nephroureterectomy with the resection of the bladder and right testicular cord, cystostomy (19.02.2015). Recurrence. Nephrostomy drainage of the left kidney. Adhesive disease. Rectovesical fistula. Taking into account the history and comorbid status of the patient, it was decided to perform laparoscopic supralevator pelvic exenteration, ureterectomy on the left. The duration of the operation was 280 minutes, intraoperative blood loss was 200 ml. The period of stay in intensive care is 24 hours, the patient was discharged on the 7th day after the operation, the resection margin was negative (R0). After 12 months, there is no data for the disease progressed.
About the Authors
E. A. GallyamovRussian Federation
Eduard A. Gallyamov – Dr. Sci., Professor, Head of the General Surgery Department
119146, Moscow, Bolshaya Pirogovskaya, 19, corp 1
15682, Moscow, Orekhovy Boulevard, 28
Leninskie Gory St., 1, 119991, Moscow
A. E. Sanzharov
Russian Federation
Andrey E. Sanzharov – head of the urological department
15682, Moscow, Orekhovy Boulevard, 28
M. A. Agapov
Russian Federation
Mikhail A. Agapov – Dr. Sci., Professor of the Department of Surgery
Leninskie Gory St., 1, 119991, Moscow
K. A. Prokhorenko
Russian Federation
Konstantin A. Prokhorenko – urologist
15682, Moscow, Orekhovy Boulevard, 28
G. Yu. Gololobov
Russian Federation
Grigorii Yu. Gololobov – surgeon; PhD student
119146, Moscow, Bolshaya Pirogovskaya, 19, corp 1
127206, Vycheticha str., 21
D. N. Doronchyk
Russian Federation
Dmitriy N. Doronchyk – urologist
15682, Moscow, Orekhovy Boulevard, 28
V. G. Daynego
Russian Federation
Vitaliy G. Daynego – urologist
15682, Moscow, Orekhovy Boulevard, 28
References
1. Luk'janov A. M., Kicenko Ju. E., Efetov S. K., Fedorov D. N., Tulina I. A., and Car'kov P. V. Mul'tidisciplinarnoe hirurgicheskoe lechenie pervichno-mnozhestvennogo raka tolstoj kishki s sohraneniem estestvennogo hoda kishechnika. Klinicheskaja i jeksperimental'naja hirurgija. vol. 7, no. 2, 2019, pp. 79-84. https://doi.org/10.24411/2308-1198-2019-12011 (In Russ)
2. Ray P, Sharifi R, Ortolano V, Guinan P. Involvement of the genito-urinary system in multiple primary malignant neoplasms: A review. J Clin Oncol. 1983; 1:574-581
3. Kit O.I., Gevorkyan Yu.A., Soldatkina N.V., Kharagezov D.A., Kolesnikov V.E., Milakin A.G. Multiple primary colorectal cancer: the possibilities of minimally invasive surgical interventions. Koloproktologia. 2017;(1):38-42. (In Russ.) https://doi.org/10.33878/2073-7556-2017-0-1-38-42
4. Teplov A.A., Grickevich A.A., Stepanova Ju.A., Miroshkina I.V., P'janikin S.S., Dunaev S.A., Arevin A.G., Morozova M.V.. "Pervichno-mnozhestvennyj rak perehodnokletochnogo jepitelija: diagnostika i osobennosti techenija zabolevanija" Jeksperimental'naja i klinicheskaja urologija, no. 4, 2018, pp. 22-29. (In Russ)
5. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. https://doi.org/10.3322/caac.21492
6. Yang TX, Morris DL, Chua TC. Pelvic exenteration for rectal cancer: A system-atic review. Dis Colon Rectum. 2013;56(4):519–31. https://doi.org/ 10.1097/DCR.0b013e31827a7868
7. Nielsen M, Rasmussen P, Pedersen B, Hagemann-Madsen R, Lindegaard J, Laurberg S. Early and Late Outcomes of Surgery for Locally Recurrent Rectal Cancer: A Prospective 10-Year Study in the Total Mesorectal Excision Era. Ann Surg Oncol. 2015;22(8):2677–84. https://doi.org/10.1245/s10434-014-4317-y
8. Volkova M.I., Matveev V.B., Medvedev S.V., Nosov D.A., Hmelevskij E.V., Chernjaev V.A. Klinicheskie rekomendacii po diagnostike i lecheniju bol'nyh s opuholjami verhnih mochevyvodjashhih putej. M., 2014; 13. (In Russ)
9. PelvEx Collaborative. Surgical and Survival Outcomes Following Pelvic Exenteration for Locally Advanced Primary Rectal Cancer: Results From an International Collaboration. Ann Surg. 2019;269(2):315–21. https://doi.org/10.1097/SLA.0000000000002528
10. Warren S, Gates O. Multiple primary malignant tumors: A survey of the literature and a statistical study. Am J Cancer. 1932; 16:1358-1414
11. Luciani A, Balducci L. Multiple primary malignancies. Semin Oncol. 2004; 31:264-273. https://doi.org/10.1053/j.seminoncol.2003.12.035
12. Vogt A, Schmid S, Heinimann K, et al. Multiple primary tumours: challenges and approaches, a review. ESMO Open 2017;2:e000172. doi:10.1136/esmoopen-2017-000172
13. Xylinas, E., et al. Multifocal Carcinoma In Situ of the Upper Tract Is Associated With High Risk of Bladder Cancer Recurrence. Eur Urol. 61: 1069.
14. Li WM, Shen JT, Li CC, Ke HL, Wei YC, Wu WJ, Chou YH, Huang CH. Oncologic outcomes following three different approaches to the distal ureter and bladder cuff in nephroureterectomy for primary upper urinary tract urothelial carcinoma. Eur Urol. 2010 Jun;57(6):963-9. https://doi.org/10.1016/j.eururo.2009.12.032
15. Rouprêt M, Yates DR, Comperat E, Cussenot O. Upper urinary tract urothelial cell carcinomas and other urological malignancies involved in the hereditary nonpolyposis colorectal cancer (lynch syndrome) tumor spectrum. European urology. 2008.1;54(6):1226-36.
16. Shirokorad V.I. Hirurgicheskoe lechenie mestnorasprostranennyh opuholej organov malogo taza . V.I. Shirokorad. – M.: OAO Izdatel'stvo "Medicina", izdatel'stvo "Shiko", 2008. (In Russian)
17. Bacalbasa N, Balescu I, Vilcu M, Neacsu A, Dima S, Croitoru A, et al. Pelvic exenteration for locally advanced and relapsed pelvic malignancies – An analysis of 100 cases. In Vivo (Brooklyn). 2019;33(6):2205–10. https://doi.org/10.21873/invivo.11723
18. Ogura A, Akiyoshi T, Konishi T, Fujimoto Y, Nagayama S, Fukunaga Y, et al. Safety of Laparoscopic Pelvic Exenteration with Urinary Diversion for Colorectal Malignancies. World J Surg. 2016;40(5):1236–43. https://doi.org/10.1007/s00268-015-3364-2
19. Uehara K, Nakamura H, Yoshino Y, Arimoto A, Kato T, Yokoyama Y, et al. Initial experience of laparoscopic pelvic exenteration and comparison with conventional open surgery. Surg Endosc. 2016;30(1):132–8. https://doi.org/10.1007/s00268-015-3364-2
20. Bizzarri N, Chiantera V, Ercoli A, Fagotti A, Tortorella L, Conte C, et al. Minimally Invasive Pelvic Exenteration for Gynecologic Malignancies: A Multi-Institutional Case Series and Review of the Literature. J Minim Invasive Gyn. 2019;26(7):1316–26. https://doi.org/10.1016/j.jmig.2018.12.019
Review
For citations:
Gallyamov E.A., Sanzharov A.E., Agapov M.A., Prokhorenko K.A., Gololobov G.Yu., Doronchyk D.N., Daynego V.G. LAPOROSCOPIC PELVIC EXENTERATION FOR TREATMENT OF PRIMARY MULTIPLE CANCER. CASE REPORT. Surgical practice (Russia). 2021;(3):31-39. (In Russ.) https://doi.org/10.38181//2223-2427-2021-3-31-39