spracticeХирургическая практикаSurgical practice (Russia)2223-2427АНО "Консорциум "Медицинская техника"10.17238/issn2223-2427.2018.1.65-68spractice-88Research ArticleСтатьиОСОБЕННОСТИ МЕТАБОЛИЗМА КОСТНОЙ ТКАНИ У ПАЦИЕНТОВ С МОРБИДНЫМ ОЖИРЕНИЕМBONE METABOLISM FEATURES IN PATIENTS WITH MORBID OBESITYЮдинВ. А.YudinV. A.vyudin@yandex.ruПанфиловаМ. С.PanfilovaM. S.panfilova.travma@gmail.comФГБОУ ВО «Рязанский государственный медицинский университет имени академика И.П. Павлова» Министерства здравоохране- ния Российской ФедерацииРоссияRyazan State Medical University named after academician I.P. PavlovRussian FederationГБУ РО “Областная клиническая больница”Россияegional Clinical HospitalRussian Federation20181504202016568Copyright © Юдин В.А., Панфилова М.С., 20202020Юдин В.А., Панфилова М.С.Yudin V.A., Panfilova M.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.spractice.ru/jour/article/view/88

В статье представлены литературные данные и результаты собственных исследований, касающиеся нарушений костного метаболизма в отда- ленном периоде после бариатрических операций. В рамках исследования изучены показатели костного метаболизма при морбидном ожирении (МО), в том числе после бариатрических вмешательств. Первую группу составили пациенты с индексом массы тела (ИМТ)> 40; вторую группу - пациенты, перенесшие бариатрические вмешательства; третью (контрольную) группу - здоровые люди, не имеющие ожирения и избыточной массы тела. Три группы различались по уровню содержания маркеров костной резорбции и показателей формирования костной ткани. В ходе исследования выявлена склонность к преобладанию процессов костной резорбции среди больных МО по сравнению с контрольной группой. Также отмечена резкая тенденция к развитию остеопенических состояний у пациентов, перенесших мальабсорбтивные типы бариатрических вмешательств, и не было выявлено данной патологии в контрольной группе. Сравнение показателей костного метаболизма в первой и второй группах подтвердило склонность к развитию остео- пороза среди оперированных пациентов, при чем у пациентов с рестриктивным типом бариатрических вмешательств с минимальным риском.

The article presents the literature data and the results of our own research concerning the violations of bone metabolism in the long term after bariatric operations. The study observed the parameters of bone metabolism in morbid obesity (MO), including the cases after bariatric interventions. The first group consist- ed of patients with a body mass index (BMI)> 40; the second group - patients who underwent bariatric interventions; the third (control) group is healthy people who do not have obesity and overweight. The three groups differed in the level of bone resorption markers and indicators of bone formation. In the course of the study, we found a tendency of prevailing of bone resorption processes among the patients with MO compared with the control group. There was also a sharp tendency towards the development of osteopenic conditions among the patients undergoing malabsorptive types of bariatric interventions, and no such pathology was revealed in the control group. The comparison of bone metabolism in the first and the second groups confirmed the tendency to develop osteoporosis among the operated patients, and in patients with restrictive type of bariatric interventions with minimal risk.

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The authors declare that there are no conflicts of interest present.