spracticeХирургическая практикаSurgical practice (Russia)2223-2427АНО "Консорциум "Медицинская техника"10.38181/2223-2427-2023-3-3spractice-412Research ArticleХИРУРГИЯSURGERYРезультаты терапии гемангиом импульсным лазером на красителе с длиной волны 595 нм и длинноимпульсного александритового лазера с длиной волны 755 нмTreatment Outcomes for Hemangiomas Using Pulsed Dye Laser (595 nm) and Long-Pulse Alexandrite Laser (755 nm)https://orcid.org/0000-0002-7245-3506СадиковР. Р.SadykovR.  R.

Расул Рустамович Садиков, доктор медицинских наук, доцент кафедры общей хирурги

100109, Ташкент, Фараби ул., 2

Rasul R. Sadykov, Assistant Professor, the Department of General Surgery

Farabi St., 2, Tashkent, 100109

rrsadykov84@gmail.comhttps://orcid.org/0000-0003-0182-3052МардоновА. С.MardonovA.  S.

Азизбек Суннатиллаевич Мардонов, хирург-колопроктолог100100, Ташкент ,ул. Малая Кольцевая, 70-А

Azizbek S. Mardonov, surgeon-coloproctologist

Kichik Halqa Yuli ,70-А, Tashkent, 100100

aziz-uz92@mail.ruhttps://orcid.org/0000-0003-0399-8892КобиловС. С.KobilovS.  S.

Саидахмад Саидакбар угли Кобилов, пластический хирург

100173, Ташкент, ул. Мукимий, 182

Saidahmad S. Kobilov, plastic surgeon

Muqimiy St., 182, Tashkent, 100173

4223323@gmail.comТашкентская Медицинская АкадемияУзбекистанTashkent Medical AcademyUzbekistanShox International HospitalУзбекистанShox International HospitalUzbekistanКлиника «Doktor Servis»УзбекистанDoktor Servis ClinicUzbekistan202307102023033242Copyright © Садиков Р.Р., Мардонов А.С., Кобилов С.С., 20232023Садиков Р.Р., Мардонов А.С., Кобилов С.С.Sadykov R.R., Mardonov A.S., Kobilov S.S.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.spractice.ru/jour/article/view/412

Цель — определить влияние 595-нм импульсного лазера на красителе и 755-нм импульсного александритового лазера на лечение гемангиом на фоне анемии.

Материалы и методы

Материалы и методы. В исследование включены 194 пациента с инфантильными гемангиомами (толщина более 2 мм и менее 8 мм), которые были случайным образом разделены на две группы: контрольную (лечение с использованием 595-нм импульсного лазера на красителе) и экспериментальную (последовательная терапия 755-нм длинноимпульсным александритовым лазером и 595-нм лазером на красителе).

Результаты

Результаты. В основной группе в 48 случаях наблюдалось полное восстановление (49,5 %), в 26 — очевидный эффект (26,8 %), в 15— улучшенный эффект (15,4 %) и в 8 — эффект увеличения (8,2 %). Эффективность лечения составила 76,3 %. В контрольной группе в 14 случаях было полное восстановление (14,4 %), в 21 — очевидный эффект (2 %), в 56 — улучшенный эффект (57,7 %) и в 6 — эффект увеличения (6,2 %). Общий коэффициент эффективности составил 36,1 %. Эффективность лечения в основной группе была выше (p < 0,05).

Выводы

Выводы. Последовательная терапия с использованием 755-нм импульсного лазера на красителе и 595-нм импульсного лазера на красителе является эффективным методом лечения гемангиом у младенцев на фоне анемии. Разработанный подход может сократить процесс лечения, что делает его применение в клинических условиях заслуживающим популяризации. Одним из факторов, мешающих повсеместному внедрению указанной методики, остается невозможность добиться идеального эффекта из-за побочных реакций, таких как рубцы.

Aim. This study aimed to evaluate the therapeutic effiacy of two laser modalities, namely a 595-nm pulsed dye laser and a 755-nm long-pulse alexandrite laser, in the treatment of hemangiomas in patients with concurrent anemia.Methods. A total of 194 patients diagnosed with infantile hemangiomas, characterized by a thickness ranging from over 2 mm to under 8 mm, were included in this study. The patients were randomly assigned to two groups: the control group received treatment with the 595-nm pulsed dye laser, while the experimental group underwent sequential therapy, beginning with the 755-nm long-pulse alexandrite laser followed by the 595-nm pulsed dye laser.Results. In the control group, the overall treatment effiacy was 36.1 %. In contrast, the experimental group exhibited a signifiantly higher effiacy of 76.3 %. Statistical analysis of the abundance data was conducted using the Chi-square (X2) test, with results deemed statistically signifiant at a signifiance level of P < .05.Conclusion. Sequential therapy, which integrates both the 755-nm pulsed dye laser and the 595-nm pulsed dye laser, demonstrates remarkable effectiveness in treating hemangiomas, particularly in cases complicated by anemia.

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The authors declare that there are no conflicts of interest present.