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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">spractice</journal-id><journal-title-group><journal-title xml:lang="ru">Хирургическая практика</journal-title><trans-title-group xml:lang="en"><trans-title>Surgical practice (Russia)</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2223-2427</issn><publisher><publisher-name>АНО "Консорциум "Медицинская техника"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.38181/issn2223-2427.2019.3.19-23</article-id><article-id custom-type="elpub" pub-id-type="custom">spractice-123</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ТРАНСДУОДЕНАЛЬНАЯ ЛАПАРОСКОПИЧЕСКАЯ ПАПИЛЛЭКТОМИЯ ПРИ АДЕНОМЕ БОЛЬШОГО ДУОДЕНАЛЬНОГО СОСОЧКА. КЛИНИЧЕСКИЙ СЛУЧАЙ</article-title><trans-title-group xml:lang="en"><trans-title>TRANSDUODENAL LAPAROSCOPIC PAPILLECTOMY FOR ADENOMA OF MAJOR DUODENAL PAPILLA. CASE REPORT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галлямов</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Galliamov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галлямов Эдуард Абдулхаевич – д.м.н., профессор, заведующий кафедрой общей хирургии</p><p>Большая Пироговская ул., д. 19 стр. 1, 119146, Москва</p></bio><bio xml:lang="en"><p>Galliamov Eduard Abdulhaevich – MD, Professor, Head of the General Surgery Department</p><p>Bolshaya Pirogovskaya St., 19/1, 119146, Moscow</p></bio><email xlink:type="simple">gal_svetlana@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Агапов</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Agapov</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Агапов Михаил Андреевич – д.м.н., профессор кафедры хирургии ФФМ</p><p>Ул. Ленинские Горы, д. 1, 119991, Москва</p></bio><bio xml:lang="en"><p>Agapov Mihail Andreevich – MD, Professor of the Department of Surgery </p><p>Leninskie Gory St., 1, 119991, Moscow</p></bio><email xlink:type="simple">getinfo911@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мальков</surname><given-names>П. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Mal’kov</surname><given-names>P. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мальков Павел Георгиевич – д.м.н., профессор, заведующий отделом клинической патологии МНОЦ</p><p>Ул. Ленинские Горы, д. 1, 119991, Москва</p></bio><bio xml:lang="en"><p>Mal’kov Pavel Georgievich – MD, Professor, Head of the Department of Clinical Patology of the Medical Research Educational Center</p><p>Leninskie Gory St., 1, 119991, Moscow</p></bio><email xlink:type="simple">malkovp@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Данилова Наталья Владимировна – к.м.н, с.н.с. отдела клинической патологии МНОЦ</p><p>Ул. Ленинские Горы, д. 1, 119991, Москва</p></bio><bio xml:lang="en"><p>Danilova Natal’ya Vladimirovna – PhD, Senior Researcher of the Department of Clinical Patology of the Medical Research Educational Center</p><p>Leninskie Gory St., 1, 119991, Moscow</p></bio><email xlink:type="simple">natalyadanilova@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Какоткин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kakotkin</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Какоткин Виктор Викторович – клинический ординатор кафедры хирургии ФФМ</p><p>Ул. Ленинские Горы, д. 1, 119991, Москва</p></bio><bio xml:lang="en"><p>Kakotkin Viktor Viktorovich - Resident of the Department of Surgery of the Faculty of Medicine</p><p>Leninskie Gory St., 1, 119991, Moscow</p></bio><email xlink:type="simple">axtroz4894@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский государственный университет имени М.В. Ломоносова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budget Educational Institution of Higher Education M.V. Lomonosov Moscow State University (Lomonosov MSU)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>18</day><month>04</month><year>2020</year></pub-date><volume>0</volume><issue>3</issue><fpage>19</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Галлямов Э.А., Агапов М.А., Мальков П.Г., Данилова Н.В., Какоткин В.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Галлямов Э.А., Агапов М.А., Мальков П.Г., Данилова Н.В., Какоткин В.В.</copyright-holder><copyright-holder xml:lang="en">Galliamov E.A., Agapov M.A., Mal’kov P.G., Danilova n.V., Kakotkin V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.spractice.ru/jour/article/view/123">https://www.spractice.ru/jour/article/view/123</self-uri><abstract><p>Мужчина (60 лет) обратился в клинику с жалобами на общую слабость, периодическое пожелтение кожных покровов. По результатам б мического анализа крови: общий билирубин – 112,5 мкмоль/л (норма 8,5-20,5 мкмоль/л), прямой билирубин – 60,8 мкмоль/л (норма 4,3-4,6 мкмоль/л), аланинаминотрансфераза (АЛТ) – 301 Ед/л (норма ≤ 30 Ед/л), аспартатаминотрансфераза (АСТ) – 95 Ед/л (норма ≤ 40 Ед/л). При выполнении эзофагогастродуоденоскопии выявлен полип большого дуоденального сосочка с признаками вовлечения в патологический процесс терминальных отделов желчного и панкреатического протоков. По данным ультразвукового исследования желчных протоков: множественный холедохолитиаз. Установлен диагноз: «Основной: Тубулярно-ворсинчатая аденома большого дуоденального сосочка с дисплазией эпителия II-III степени. Осложнение основного заболевания: множественный холедохолитиаз. Механическая желтуха. Печеночная недостаточность». Выполнена операция: лапароскопия, дуоденотомия, папиллэктомия с формированием холедоховирсунгодуоденоанастомоза и ушиванием дефекта задней стенки двенадцатиперстной кишки, холедохолитотомия, дуоденопластика, дренирование брюшной полости. Течение послеоперационного периода без осложнений. Полипы большого дуоденального сосочка – сравнительно редкая форма новообразований желудочно-кишечного тракта, которые могут не проявляться клинически, либо, как в вышеописанном случае, могут приводить к тяжёлым патологическим состояниям. В настоящее время не существует единого подхода к лечению данной группы заболеваний. Хирургическое вмешательство является единственным радикальным методом лечения полипов большого дуоденального сосочка. Некоторые авторы предлагают проведение панкреатодуоденальной резекции, однако риски данной операции, связанные с тяжестью и травматичностью последней, не всегда оправданы. Представленный случай является уникальным ввиду того, что выполненная пациенту операция является менее инвазивной по сравнению с панкреатодуоденальной резекцией и затрагивает минимальное количество органов. Лапароскопический подход имеет существенные преимущества в лечении этой нечастой патологии.</p></abstract><trans-abstract xml:lang="en"><p>A 60-year-old man admitted to the clinical center due to weakness, episodes of jaundice. The laboratory date revealed elevated levels of total bilirubin - 112.5 µmol/l (range 8,5-20,5 µmol/l) and direct bilirubin - 60.8 µmol/l (range 4,3-4,6 µmol/l), elevated hepatic enzymes (aspartate aminotransferase [AST]: 95 U/l (range ≤ 40 U/L), alanine aminotransferase [ALT]: 301 U/l (range ≤ 30 U/L). When performing esophagogastroduodenoscopy, a polyp of the large duodenal papilla with a spread to the terminal parts of the bile and pancreatic ducts was revealed, and a biopsy was taken. Diagnisis: "Tubulovillous adenoma of the major duodenal papilla with epithelial dysplasia II-III". Complications: "Multiple choledocholithiasis. Mechanical jaundice. Liver failure." Surgery: laparoscopic duodenotomy, papillectomy, choledocholithotomy, performing of choledochoduodenal anastomosis, duodenoplasty and abdominal drainage. The postoperative period was taking its normal course. Polyps of the large duodenal papilla are relatively rare form of tumors of the gastrointestinal tract, which may not manifest clinically, or, as the above case, lead to severe pathological conditions. Currently, there is no single approach to the treatment of this group of diseases. Some authors propose a pancreatoduodenal resection, but the risks of this operation associated with high postoperative morbidity and mortality are not always justified. The case is unique because the described procedure is less invasive and affects the minimum number of organs. Laparoscopic approach has significant advantages in the treatment of this infrequent pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трансдуоденальная папиллэктомия</kwd><kwd>большой дуоденальный сосочек</kwd><kwd>лапароскопическая дуоденотомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tranduodenal papillectomy</kwd><kwd>large duodenal papilla</kwd><kwd>laparoscopic du-odenotomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Виноградов В.В., Базилевич Ф.В. Полипы большого дуоденального сосочка // Вестник хирургии. 1977. 118(3). С. 46-50.</mixed-citation><mixed-citation xml:lang="en">Vinogradov VV, Bazilevich FV. Polyps of the large duodenal papilla. 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